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Mitochondrial common deletion is elevated in blood of breast cancer patients mediated by oxidative stress

The 4,977 bp common deletion is one of the most frequently observed mitochondrial DNA (mtDNA) mutations in human tissues and has been implicated in various human cancer types. It is generally believed that continuous generation of intracellular reactive oxygen species (ROS) during oxidative phosphor...

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Detalhes bibliográficos
Publicado no:Mitochondrion
Main Authors: Nie, Hezhongrong, Chen, Guorong, He, Jing, Zhang, Fengjiao, Li, Ming, Wang, Qiufeng, Zhou, Huaibing, Lyu, Jianxin, Bai, Yidong
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4846287/
https://ncbi.nlm.nih.gov/pubmed/26678158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2015.12.001
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