Transgenic Overexpression of Tissue‐Nonspecific Alkaline Phosphatase (TNAP) in Vascular Endothelium Results in Generalized Arterial Calcification

BACKGROUND: Ectopic vascular calcification is a common condition associated with aging, atherosclerosis, diabetes, and/or chronic kidney disease. Smooth muscle cells are the best characterized source of osteogenic progenitors in the vasculature; however, recent studies suggest that cells of endothel...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Savinov, Alexei Y., Salehi, Maryam, Yadav, Manisha C., Radichev, Ilian, Millán, José Luis, Savinova, Olga V.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845279/
https://ncbi.nlm.nih.gov/pubmed/26675253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.115.002499
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