Tissue Nonspecific Alkaline Phosphatase (TNAP) Regulates Cranial Base Growth and Synchondrosis Maturation

Hypophosphatasia is a rare heritable disorder caused by inactivating mutations in the gene (Alpl) that encodes tissue nonspecific alkaline phosphatase (TNAP). Hypophosphatasia with onset in infants and children can manifest as rickets. How TNAP deficiency leads to bone hypomineralization is well exp...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Physiol
Prif Awduron: Nam, Hwa K., Sharma, Monika, Liu, Jin, Hatch, Nan E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2017
Pynciau:
Physiology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5359511/
https://ncbi.nlm.nih.gov/pubmed/28377728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00161
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