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p185c-neu and epidermal growth factor receptor associate into a structure composed of activated kinases.

The protein product of the neu protooncogene, p185c-neu, is structurally similar to the epidermal growth factor receptor (EGFR). Overexpression of these two receptor tyrosine kinases, but not either separately, leads to transformation and tumorigenicity. Heterodimerization of p185c-neu and EGFR occu...

詳細記述

保存先:
書誌詳細
主要な著者: Quian, X L, Decker, S J, Greene, M I
フォーマット: Artigo
言語:Inglês
出版事項: 1992
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC48443/
https://ncbi.nlm.nih.gov/pubmed/1346931
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