Ligand and p185c-neu density govern receptor interactions and tyrosine kinase activation.
The neu protooncogene (also known as c-erbB2, NGL, and HER2) encodes a 185-kDa transmembrane glycoprotein with intrinsic tyrosine kinase activity that resembles the receptor for epidermal growth factor. The p185 gene and protein were originally identified in the brain and are thought to play a criti...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1994
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43233/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7907421/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.5.1711 |
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