p185c-neu and epidermal growth factor receptor associate into a structure composed of activated kinases.

The protein product of the neu protooncogene, p185c-neu, is structurally similar to the epidermal growth factor receptor (EGFR). Overexpression of these two receptor tyrosine kinases, but not either separately, leads to transformation and tumorigenicity. Heterodimerization of p185c-neu and EGFR occu...

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Bibliografski detalji

Izdano u:	Proc Natl Acad Sci U S A
Glavni autori:	Quian, X L, Decker, S J, Greene, M I
Format:	Artigo
Jezik:	Inglês
Izdano:	National Academy of Sciences 1992
Teme:	Research Article
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48443/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1346931/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.4.1330
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