A carregar...
Towards “bionic” proteins: replacement of continuous sequences from HIF-1α with proteomimetics to create functional p300 binding HIF-1α mimics
Using the HIF-1α transcription factor as a model, this manuscript illustrates how an extended sequence of α-amino acids in a polypeptide can be replaced with a non-natural topographical mimic of an α-helix comprised from an aromatic oligoamide. The resultant hybrid is capable of reproducing the mole...
Na minha lista:
| Publicado no: | Chem Commun (Camb) |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Royal Society of Chemistry
2016
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4843846/ https://ncbi.nlm.nih.gov/pubmed/27009828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6cc01812b |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|