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Structural Basis for the Interaction between Pyk2-FAT Domain and Leupaxin LD Repeats
[Image: see text] Proline-rich tyrosine kinase 2 (Pyk2) is a nonreceptor tyrosine kinase and belongs to the focal adhesion kinase (FAK) family. Like FAK, the C-terminal focal adhesion-targeting (FAT) domain of Pyk2 binds to paxillin, a scaffold protein in focal adhesions; however, the interaction be...
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| Publicado no: | Biochemistry |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American
Chemical Society
2016
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4843776/ https://ncbi.nlm.nih.gov/pubmed/26866573 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b01274 |
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