Saxagliptin and Tadalafil Differentially Alter Cyclic Guanosine Monophosphate (cGMP) Signaling and Left Ventricular Function in Aortic‐Banded Mini‐Swine

BACKGROUND: Cyclic guanosine monophosphate‐protein kinase G‐phosphodiesterase 5 signaling may be disturbed in heart failure (HF) with preserved ejection fraction, contributing to cardiac remodeling and dysfunction. The purpose of this study was to manipulate cyclic guanosine monophosphate signaling...

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Bibliografiske detaljer
Udgivet i:J Am Heart Assoc
Main Authors: Hiemstra, Jessica A., Lee, Dong I., Chakir, Khalid, Gutiérrez‐Aguilar, Manuel, Marshall, Kurt D., Zgoda, Pamela J., Cruz Rivera, Noelany, Dozier, Daniel G., Ferguson, Brian S., Heublein, Denise M., Burnett, John C., Scherf, Carolin, Ivey, Jan R., Minervini, Gianmaria, McDonald, Kerry S., Baines, Christopher P., Krenz, Maike, Domeier, Timothy L., Emter, Craig A.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4843537/
https://ncbi.nlm.nih.gov/pubmed/27098966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.116.003277
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