Saxagliptin and Tadalafil Differentially Alter Cyclic Guanosine Monophosphate (cGMP) Signaling and Left Ventricular Function in Aortic‐Banded Mini‐Swine

BACKGROUND: Cyclic guanosine monophosphate‐protein kinase G‐phosphodiesterase 5 signaling may be disturbed in heart failure (HF) with preserved ejection fraction, contributing to cardiac remodeling and dysfunction. The purpose of this study was to manipulate cyclic guanosine monophosphate signaling...

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Библиографические подробности
Опубликовано в: :J Am Heart Assoc
Главные авторы: Hiemstra, Jessica A., Lee, Dong I., Chakir, Khalid, Gutiérrez‐Aguilar, Manuel, Marshall, Kurt D., Zgoda, Pamela J., Cruz Rivera, Noelany, Dozier, Daniel G., Ferguson, Brian S., Heublein, Denise M., Burnett, John C., Scherf, Carolin, Ivey, Jan R., Minervini, Gianmaria, McDonald, Kerry S., Baines, Christopher P., Krenz, Maike, Domeier, Timothy L., Emter, Craig A.
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2016
Предметы:
Original Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4843537/
https://ncbi.nlm.nih.gov/pubmed/27098966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.116.003277
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