טוען...
Inhibition of PDE5A1 guanosine cyclic monophosphate (cGMP) hydrolysing activity by sildenafil analogues that inhibit cellular cGMP efflux
OBJECTIVES: To determine the ability of 11 sildenafil analogues to discriminate between cyclic nucleotide phosphodiesterases (cnPDEs) and to characterise their inhibitory potencies (K (i) values) of PDE5A1‐dependent guanosine cyclic monophosphate (cGMP) hydrolysis. METHODS: Sildenafil analogues were...
שמור ב:
| הוצא לאור ב: | J Pharm Pharmacol |
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| Main Authors: | , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
John Wiley and Sons Inc.
2017
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5434896/ https://ncbi.nlm.nih.gov/pubmed/28211580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jphp.12693 |
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