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Functional Characterization of Human CYP2C9 Allelic Variants in COS-7 Cells
Variability in activity of CYP2C9, which is involved in the metabolism of approximately 15% of current therapeutic drugs, is an important contributor to interindividual differences in drug response. To evaluate the functional alternations of CYP2C9(*)2, CYP2C9(*)3, CYP2C9(*)8, CYP2C9(*)11 and CYP2C9...
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| Опубликовано в: : | Front Pharmacol |
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| Главные авторы: | , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Frontiers Media S.A.
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4843492/ https://ncbi.nlm.nih.gov/pubmed/27199745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2016.00098 |
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