A Systematically Combined Genotype and Functional Combination Analysis of CYP2E1, CYP2D6, CYP2C9, CYP2C19 in Different Geographic Areas of Mainland China – A Basis for Personalized Therapy

The cytochrome P450 is the major enzyme involved in drug metabolism. Single CYP genotypes and metabolic phenotypes have been widely studied, but no combination analysis has been conducted in the context of specific populations and geographical areas. This study is the first to systematically analyze...

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Hauptverfasser: Wu, Zhenqiang, Zhang, Xiaoqing, Shen, Lu, Xiong, Yuyu, Wu, Xi, Huo, Ran, Wei, Zhiyun, Cai, Lei, Qi, Guoyang, Xu, Qingqing, Cui, Daxiang, Cui, Donghong, Zhao, Gengchun, He, Lin, Qin, Shengying
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3788764/
https://ncbi.nlm.nih.gov/pubmed/24098323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071934
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