Frequency of CYP2D6 Alleles Including Structural Variants in the United States

The CYP2D6 gene encodes an enzyme important in the metabolism of many commonly used medications. Variation in CYP2D6 is associated with inter-individual differences in medication response, and genetic testing is used to optimize medication therapy. This report describes a retrospective study of CYP2...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Del Tredici, Andria L., Malhotra, Alka, Dedek, Matthew, Espin, Frank, Roach, Dan, Zhu, Guang-dan, Voland, Joseph, Moreno, Tanya A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5895772/
https://ncbi.nlm.nih.gov/pubmed/29674966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00305
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