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CYP2D6 allele frequencies, copy number variants, and tandems in the population of Hong Kong

BACKGROUND: CYP2D6 plays a crucial role in drug metabolism of several drugs. It is known to be highly polymorphic with enzymatic activity ranging from poor to ultrarapid metabolic rates. While the frequencies of CYP2D6 alleles are generally known in different Asian populations, data on frequencies o...

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Detalhes bibliográficos
Publicado no:J Clin Lab Anal
Main Authors: Chan, Wing, Li, Man S., Sundaram, Senthil K., Tomlinson, Brian, Cheung, Pik Y., Tzang, Chi H.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6430334/
https://ncbi.nlm.nih.gov/pubmed/30069923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcla.22634
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