Integrated CYP2D6 interrogation for multiethnic copy number and tandem allele detection

AIM: To comprehensively interrogate CYP2D6 by integrating genotyping, copy number analysis and novel strategies to identify CYP2D6*36 and characterize CYP2D6 duplications. METHODS: Genotyping of 16 CYP2D6 alleles, multiplex ligation-dependent probe amplification (MLPA) and CYP2D6*36 and duplication...

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Detalhes bibliográficos
Publicado no:Pharmacogenomics
Main Authors: Qiao, Wanqiong, Martis, Suparna, Mendiratta, Geetu, Shi, Lisong, Botton, Mariana R, Yang, Yao, Gaedigk, Andrea, Vijzelaar, Raymon, Edelmann, Lisa, Kornreich, Ruth, Desnick, Robert J, Scott, Stuart A
Formato: Artigo
Idioma:Inglês
Publicado em: Future Medicine Ltd 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6563015/
https://ncbi.nlm.nih.gov/pubmed/30730286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs-2018-0135
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