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A Screening Test for HLA-B(∗)15:02 in a Large United States Patient Cohort Identifies Broader Risk of Carbamazepine-Induced Adverse Events
Purpose: HLA-B(∗)15:02 is strongly associated with life-threatening severe skin hypersensitivity reactions in patients treated with carbamazepine (CBZ) and structurally related medications. FDA-approved labeling recommends HLA-B(∗)15:02 screening before CBZ therapy in patients of Asian ancestry. In...
שמור ב:
| הוצא לאור ב: | Front Pharmacol |
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| Main Authors: | , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Frontiers Media S.A.
2019
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6443844/ https://ncbi.nlm.nih.gov/pubmed/30971914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00149 |
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