Carbamazepine-Mediated Adverse Drug Reactions: CBZ-10,11-epoxide but Not Carbamazepine Induces the Alteration of Peptides Presented by HLA-B∗15:02

Among patients treated with the anticonvulsive and psychotropic drug carbamazepine (CBZ), approximately 10% develop severe and life-threatening adverse drug reactions. These immunological conditions are resolved upon withdrawal of the medicament, suggesting that the drug does not manifest in the bod...

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Detalhes bibliográficos
Publicado no:J Immunol Res
Main Authors: Simper, Gwendolin S., Hò, Gia-Gia T., Celik, Alexander A., Huyton, Trevor, Kuhn, Joachim, Kunze-Schumacher, Heike, Blasczyk, Rainer, Bade-Döding, Christina
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158965/
https://ncbi.nlm.nih.gov/pubmed/30302345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/5086503
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