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NKG2A/CD94 Is a New Immune Receptor for HLA-G and Distinguishes Amino Acid Differences in the HLA-G Heavy Chain

Natural killer (NK) cell therapies are a tool to antagonize a dysfunctional immune system. NK cells recognize malignant cells, traffic to a tumor location, and infiltrate the solid tumor. The immune checkpoint molecule human leukocyte antigen (HLA)-G is upregulated on malignant cells but not on heal...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Hò, Gia-Gia T., Celik, Alexander A., Huyton, Trevor, Hiemisch, Wiebke, Blasczyk, Rainer, Simper, Gwendolin S., Bade-Doeding, Christina
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352787/
https://ncbi.nlm.nih.gov/pubmed/32575403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21124362
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