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Distribution of allelic and genotypic frequencies of NAT2 and CYP2E1 variants in Moroccan population
BACKGROUND: Several pathogenesis and genetic factors influence predisposition to antituberculosis drug-induced hepatotoxicity (ATDH) especially for isoniazid (INH). However, the major susceptibility genes for ATDH are N-acetyltransferase 2 (NAT2) and cytochrome P450 2E1 (CYP2E1). NAT2 gene determine...
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| Publicado no: | BMC Genet |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4299568/ https://ncbi.nlm.nih.gov/pubmed/25544508 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-014-0156-x |
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