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Novel nonsense mutation of BRCA2 gene in a Moroccan man with familial breast cancer

BACKGROUND: Breast cancer is the most common cancer in women worldwide. About 5 to 10% of cases are due to an inherited predisposition in two major genes, BRCA1 and BRCA2, transmitted as an autosomal dominant form. Male breast cancer is rare and is mainly due to BRCA2 than BRCA1 germline mutations....

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Detalhes bibliográficos
Main Authors: Guaoua, Soukaina, Ratbi, Ilham, Lyahyai, Jaber, El Alaoui, Siham Chafai, Laarabi, Fatima-Zahra, Sefiani, Abdelaziz
Formato: Artigo
Idioma:Inglês
Publicado em: Makerere Medical School 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196389/
https://ncbi.nlm.nih.gov/pubmed/25320599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4314/ahs.v14i2.25
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