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First application of next-generation sequencing in Moroccan breast/ovarian cancer families and report of a novel frameshift mutation of the BRCA1 gene

At present, breast cancer is the most common type of cancer in females. The majority of cases are sporadic, but 5–10% are due to an inherited predisposition to develop breast and ovarian cancers, which are transmitted as an autosomal dominant form with incomplete penetrance. The beneficial effects o...

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Bibliografske podrobnosti
izdano v:Oncol Lett
Main Authors: Jouali, Farah, Laarabi, Fatima-Zahra, Marchoudi, Nabila, Ratbi, Ilham, Elalaoui, Siham Chafai, Rhaissi, Houria, Fekkak, Jamal, Sefiani, Abdelaziz
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4950805/
https://ncbi.nlm.nih.gov/pubmed/27446417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2016.4739
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