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A strategy for the generation of conditional mutations by protein destabilization.

Conditional mutations such as temperature-sensitive (ts) mutations are important for the analysis of protein function but are often difficult, or impossible, to obtain. Here we present a simple method for generating conditional mutations based on the use of a protein-destabilizing genetic element in...

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Hlavní autoři: Park, E C, Finley, D, Szostak, J W
Médium: Artigo
Jazyk:Inglês
Vydáno: 1992
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC48426/
https://ncbi.nlm.nih.gov/pubmed/1311090
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