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Strategies to Achieve Conditional Gene Mutation in Mice

The laboratory mouse is an ideal model organism for studying disease because it is physiologically similar to human and also because its genome is readily manipulated. Genetic engineering allows researchers to introduce specific loss-of-function or gain-of-function mutations into genes and then to s...

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Bibliografische gegevens
Hoofdauteurs: Gierut, Jessica J., Jacks, Tyler E., Haigis, Kevin M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4142476/
https://ncbi.nlm.nih.gov/pubmed/24692485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/pdb.top069807
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