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Strategies to Achieve Conditional Gene Mutation in Mice
The laboratory mouse is an ideal model organism for studying disease because it is physiologically similar to human and also because its genome is readily manipulated. Genetic engineering allows researchers to introduce specific loss-of-function or gain-of-function mutations into genes and then to s...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4142476/ https://ncbi.nlm.nih.gov/pubmed/24692485 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/pdb.top069807 |
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