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A strategy for the generation of conditional mutations by protein destabilization.

Conditional mutations such as temperature-sensitive (ts) mutations are important for the analysis of protein function but are often difficult, or impossible, to obtain. Here we present a simple method for generating conditional mutations based on the use of a protein-destabilizing genetic element in...

詳細記述

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書誌詳細
主要な著者: Park, E C, Finley, D, Szostak, J W
フォーマット: Artigo
言語:Inglês
出版事項: 1992
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC48426/
https://ncbi.nlm.nih.gov/pubmed/1311090
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