RPA alleviates the inhibitory effect of vinylphosphonate internucleotide linkages on DNA unwinding by BLM and WRN helicases

Bloom (BLM) and Werner (WRN) syndrome proteins are members of the RecQ family of SF2 DNA helicases. In this paper, we show that restricting the rotational DNA backbone flexibility, by introducing vinylphosphonate internucleotide linkages in the translocating DNA strand, inhibits efficient duplex unw...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	Nucleic Acids Res
Päätekijät:	Garcia, Patrick L., Bradley, Glyn, Hayes, Christopher J., Krintel, Sussie, Soultanas, Panos, Janscak, Pavel
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Oxford University Press 2004
Aiheet:	Articles
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC484189/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15256542/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkh709
Tagit:	Lisää tagi Ei tageja, Lisää ensimmäinen tagi!