RPA alleviates the inhibitory effect of vinylphosphonate internucleotide linkages on DNA unwinding by BLM and WRN helicases

Bloom (BLM) and Werner (WRN) syndrome proteins are members of the RecQ family of SF2 DNA helicases. In this paper, we show that restricting the rotational DNA backbone flexibility, by introducing vinylphosphonate internucleotide linkages in the translocating DNA strand, inhibits efficient duplex unw...

Descripció completa

Dades bibliogràfiques

Publicat a:	Nucleic Acids Res
Autors principals:	Garcia, Patrick L., Bradley, Glyn, Hayes, Christopher J., Krintel, Sussie, Soultanas, Panos, Janscak, Pavel
Format:	Artigo
Idioma:	Inglês
Publicat:	Oxford University Press 2004
Matèries:	Articles
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC484189/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15256542/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkh709
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!