Zoledronate upregulates MMP-9 and -13 in rat vascular smooth muscle cells by inducing oxidative stress

BACKGROUND: Bisphosphonates, including zoledronate, target osteoclasts and are widely used in the treatment of osteoporosis and other bone resorption diseases, despite side effects that include damaging the stomach epithelium. Beneficial and adverse effects on other organ systems, including the card...

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Bibliografiska uppgifter
I publikationen:Drug Des Devel Ther
Huvudupphovsmän: Arun, Mehmet Zuhuri, Reel, Buket, Sala-Newby, Graciela B, Bond, Mark, Tsaousi, Aikaterini, Maskell, Perry, Newby, Andrew C
Materialtyp: Artigo
Språk:Inglês
Publicerad: Dove Medical Press 2016
Ämnen:
Original Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4841407/
https://ncbi.nlm.nih.gov/pubmed/27143852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S103124
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