The Hippo pathway mediates inhibition of vascular smooth muscle cell proliferation by cAMP

AIMS: Inhibition of vascular smooth muscle cell (VSMC) proliferation by intracellular cAMP prevents excessive neointima formation and hence angioplasty restenosis and vein-graft failure. These protective effects are mediated via actin-cytoskeleton remodelling and subsequent regulation of gene expres...

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Dettagli Bibliografici
Pubblicato in:J Mol Cell Cardiol
Autori principali: Kimura, Tomomi E., Duggirala, Aparna, Smith, Madeleine C., White, Stephen, Sala-Newby, Graciela B., Newby, Andrew C., Bond, Mark
Natura: Artigo
Lingua:Inglês
Pubblicazione: Academic Press 2016
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727789/
https://ncbi.nlm.nih.gov/pubmed/26625714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2015.11.024
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