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cAMP-induced actin cytoskeleton remodelling inhibits MKL1-dependent expression of the chemotactic and pro-proliferative factor, CCN1

Elevation of intracellular cAMP concentration has numerous vascular protective effects that are in part mediated via actin cytoskeleton-remodelling and subsequent regulation of gene expression. However, the mechanisms are incompletely understood. Here we investigated whether cAMP-induced actin-cytos...

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Detalles Bibliográficos
Publicado en:J Mol Cell Cardiol
Main Authors: Duggirala, Aparna, Kimura, Tomomi E., Sala-Newby, Graciela B., Johnson, Jason L., Wu, Yih-Jer, Newby, Andrew C., Bond, Mark
Formato: Artigo
Idioma:Inglês
Publicado: Academic Press 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4312355/
https://ncbi.nlm.nih.gov/pubmed/25446180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2014.11.012
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