Dual Role of CREB in The Regulation of VSMC Proliferation: Mode of Activation Determines Pro- or Anti-Mitogenic Function

Vascular smooth muscle cell (VSMC) proliferation has been implicated in the development of restenosis after angioplasty, vein graft intimal thickening and atherogenesis. We investigated the mechanisms underlying positive and negative regulation of VSMC proliferation by the transcription factor cycli...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hudson, Claire, Kimura, Tomomi E., Duggirala, Aparna, Sala-Newby, Graciela B., Newby, Andrew C., Bond, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5861041/
https://ncbi.nlm.nih.gov/pubmed/29559698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23199-4
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