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TGF-β suppresses the upregulation of MMP-2 by vascular smooth muscle cells in response to PDGF-BB

During platelet-derived growth factor (PDGF)-BB-mediated recruitment to neovascular sprouts, vascular smooth muscle cells (VSMCs) dedifferentiate from a contractile to a migratory phenotype. This involves the downregulation of contractile markers such as smooth muscle (SM) α-actin and the upregulati...

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Detalhes bibliográficos
Main Authors: Risinger, George M., Updike, Dawn L., Bullen, Elizabeth C., Tomasek, James J., Howard, Eric W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806150/
https://ncbi.nlm.nih.gov/pubmed/19846754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00417.2008
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