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TGF-β suppresses the upregulation of MMP-2 by vascular smooth muscle cells in response to PDGF-BB
During platelet-derived growth factor (PDGF)-BB-mediated recruitment to neovascular sprouts, vascular smooth muscle cells (VSMCs) dedifferentiate from a contractile to a migratory phenotype. This involves the downregulation of contractile markers such as smooth muscle (SM) α-actin and the upregulati...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Physiological Society
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2806150/ https://ncbi.nlm.nih.gov/pubmed/19846754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00417.2008 |
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