The Regulation of Matrix Metalloproteinase Expression and the Role of Discoidin Domain Receptor 1/2 Signalling in Zoledronate-treated PC3 Cells

Discoidin Domain Receptors (DDR1/DDR2) are tyrosine kinase receptors which are activated by collagen. DDR signalling regulates cell migration, proliferation, apoptosis and matrix metalloproteinase (MMP) production. MMPs degrade extracellular matrix (ECM) and play essential role in tumor growth, inva...

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Detalhes bibliográficos
Publicado no:J Cancer
Main Authors: Reel, Buket, Korkmaz, Ceren Gonen, Arun, Mehmet Zuhuri, Yildirim, Gokce, Ogut, Deniz, Kaymak, Aysegul, Micili, Serap Cilaker, Ergur, Bekir Ugur
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4565852/
https://ncbi.nlm.nih.gov/pubmed/26366216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.12733
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