The Regulation of Matrix Metalloproteinase Expression and the Role of Discoidin Domain Receptor 1/2 Signalling in Zoledronate-treated PC3 Cells

Discoidin Domain Receptors (DDR1/DDR2) are tyrosine kinase receptors which are activated by collagen. DDR signalling regulates cell migration, proliferation, apoptosis and matrix metalloproteinase (MMP) production. MMPs degrade extracellular matrix (ECM) and play essential role in tumor growth, inva...

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Библиографические подробности
Опубликовано в: :J Cancer
Главные авторы: Reel, Buket, Korkmaz, Ceren Gonen, Arun, Mehmet Zuhuri, Yildirim, Gokce, Ogut, Deniz, Kaymak, Aysegul, Micili, Serap Cilaker, Ergur, Bekir Ugur
Формат: Artigo
Язык:Inglês
Опубликовано: Ivyspring International Publisher 2015
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4565852/
https://ncbi.nlm.nih.gov/pubmed/26366216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.12733
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