Photoreceptor-targeted gene delivery using intravitreally administered AAV vectors in dogs

Delivery of therapeutic transgenes to retinal photoreceptors using adeno-associated virus (AAV) vectors has traditionally required subretinal injection. Recently, photoreceptor transduction efficiency following intravitreal injection (IVT) has improved in rodent models through use of capsid-mutant A...

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Bibliografiska uppgifter
I publikationen:Gene Ther
Huvudupphovsmän: Boyd, RF, Sledge, DG, Boye, SL, Boye, SE, Hauswirth, WW, Komáromy, AM, Petersen-Jones, SM, Bartoe, JT
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4840844/
https://ncbi.nlm.nih.gov/pubmed/26467396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2015.96
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