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Use of the DNA Fiber Spreading Technique to Detect the Effects of Mutant p53 on DNA Replication

DNA replication involves a coordinated progression through S phase, and disruption of these regulated steps may cause gene abnormalities, which may lead to cancer. Different stages of DNA replication can be detected immunofluorescently that would indicate how replication is progressing in a cell pop...

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Detalhes bibliográficos
Publicado no:Methods Mol Biol
Main Authors: Frum, Rebecca A., Deb, Sumitra, Deb, Swati Palit
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839281/
https://ncbi.nlm.nih.gov/pubmed/23150444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-62703-236-0_12
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