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Use of the DNA Fiber Spreading Technique to Detect the Effects of Mutant p53 on DNA Replication
DNA replication involves a coordinated progression through S phase, and disruption of these regulated steps may cause gene abnormalities, which may lead to cancer. Different stages of DNA replication can be detected immunofluorescently that would indicate how replication is progressing in a cell pop...
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| Pubblicato in: | Methods Mol Biol |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4839281/ https://ncbi.nlm.nih.gov/pubmed/23150444 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-62703-236-0_12 |
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