Structural characterization of NRAS isoform 5

It was recently discovered that the NRAS isoform 5 (20 amino acids) is expressed in melanoma and results in a more aggressive cell phenotype. This novel isoform is responsible for increased phosphorylation of downstream targets such as AKT, MEK, and ERK as well as increased cellular proliferation. T...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Protein Sci
Main Authors: Markowitz, Joseph, Mal, Tapas K., Yuan, Chunhua, Courtney, Nicholas B., Patel, Mitra, Stiff, Andrew R., Blachly, James, Walker, Christopher, Eisfeld, Ann‐Kathrin, de la Chapelle, Albert, Carson, William E.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2016
Assuntos:
Protein Structure Reports
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838646/
https://ncbi.nlm.nih.gov/pubmed/26947772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2916
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares