MicroRNA-3151 inactivates TP53 in BRAF-mutated human malignancies

The B-Raf proto-oncogene serine/threonine kinase (BRAF) gene is the most frequently mutated gene in malignant melanoma (MM) and papillary thyroid cancer (PTC) and is causally involved in malignant cell transformation. Mutated BRAF is associated with an aggressive disease phenotype, thus making it a...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Lankenau, Malori A., Patel, Ravi, Liyanarachchi, Sandya, Maharry, Sophia E., Hoag, Kevin W., Duggan, Megan, Walker, Christopher J., Markowitz, Joseph, Carson, William E., Eisfeld, Ann-Kathrin, de la Chapelle, Albert
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679059/
https://ncbi.nlm.nih.gov/pubmed/26582795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1520390112
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados