Dissection of the major hematopoietic quantitative trait locus in chromosome 6q23.3 identifies miR-3662 as a novel player in hematopoiesis and acute myeloid leukemia

Chromosomal aberrations and multiple genome-wide association studies (GWASs) have established a major hematopoietic quantitative trait locus in chromosome 6q23.3. The locus comprises an active enhancer region, in which some of the associated SNPs alter transcription factor binding. We now identify m...

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Publicado no:Cancer Discov
Main Authors: Maharry, Sophia E., Walker, Christopher J., Liyanarachchi, Sandya, Mehta, Sujay, Patel, Mitra, Bainazar, Maryam A., Huang, Xiaomeng, Lankenau, Malori A., Hoag, Kevin W., Ranganathan, Parvathi, Garzon, Ramiro, Blachly, James S., Guttridge, Denis C., Bloomfield, Clara D., de la Chapelle, Albert, Eisfeld, Ann-Kathrin
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5168803/
https://ncbi.nlm.nih.gov/pubmed/27354268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-16-0023
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