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Problems and solutions for the analysis of somatic CAG repeat expansion and their relationship to Huntington's disease toxicity
Huntington's Disease is caused by inheritance of a single disease-length allele harboring an expanded CAG repeat, which continues to expand in somatic tissues with age. Whether somatic expansion contributed to toxicity was unknown. From extensive work from multiple laboratories, it has been mad...
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| Publicado en: | Rare Dis |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Taylor & Francis
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4838321/ https://ncbi.nlm.nih.gov/pubmed/27141411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21675511.2015.1131885 |
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