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The Contribution of Somatic Expansion of the CAG Repeat to Symptomatic Development in Huntington’s Disease: A Historical Perspective

The discovery in the early 1990s of the expansion of unstable simple sequence repeats as the causative mutation for a number of inherited human disorders, including Huntington’s disease (HD), opened up a new era of human genetics and provided explanations for some old problems. In particular, an inv...

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Detaylı Bibliyografya
Yayımlandı:J Huntingtons Dis
Yazar: Monckton, Darren G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: IOS Press 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7990401/
https://ncbi.nlm.nih.gov/pubmed/33579863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JHD-200429
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