Neuronal ensembles sufficient for recovery sleep and the sedative actions of α(2) adrenergic agonists

Do sedatives engage natural sleep pathways? It is usually assumed that anesthetic-induced sedation and loss-of-righting-reflex (LORR) arise by influencing the same circuitry to lesser or greater extents. For the α2 adrenergic receptor agonist dexmedetomidine, we find that sedation and LORR are in fa...

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Udgivet i:Nat Neurosci
Main Authors: Zhang, Zhe, Ferretti, Valentina, Güntan, İlke, Moro, Alessandro, Steinberg, Eleonora A., Ye, Zhiwen, Zecharia, Anna Y., Yu, Xiao, Vyssotski, Alexei L., Brickley, Stephen G., Yustos, Raquel, Pillidge, Zoe E., Harding, Edward C., Wisden, William, Franks, Nicholas P.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836567/
https://ncbi.nlm.nih.gov/pubmed/25706476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3957
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