Excitatory Pathways from the Lateral Habenula Enable Propofol-Induced Sedation

The lateral habenula has been widely studied for its contribution in generating reward-related behaviors [1, 2]. We have found that this nucleus plays an unexpected role in the sedative actions of the general anesthetic propofol. The lateral habenula is a glutamatergic, excitatory hub that projects...

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Gepubliceerd in:Curr Biol
Hoofdauteurs: Gelegen, Cigdem, Miracca, Giulia, Ran, Mingzi Z., Harding, Edward C., Ye, Zhiwen, Yu, Xiao, Tossell, Kyoko, Houston, Catriona M., Yustos, Raquel, Hawkins, Edwin D., Vyssotski, Alexei L., Dong, Hailong L., Wisden, William, Franks, Nicholas P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cell Press 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5835141/
https://ncbi.nlm.nih.gov/pubmed/29398217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2017.12.050
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