Inhibition of class I histone deacetylases blunts cardiac hypertrophy through TSC2-dependent mTOR repression

Altering chromatin structure through histone posttranslational modifications has emerged as a key driver of transcriptional responses in cells. Modulation of these transcriptional responses by pharmacological inhibition of class I histone deacetylases (HDACs), a group of chromatin remodeling enzymes...

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Detaylı Bibliyografya
Yayımlandı:Sci Signal
Asıl Yazarlar: Morales, Cyndi R., Li, Dan L., Pedrozo, Zully, May, Herman I., Jiang, Nan, Kyrychenko, Viktoriia, Cho, Geoffrey, Kim, Soo Young, Wang, Zhao V., Rotter, David, Rothermel, Beverly A., Schneider, Jay W., Lavandero, Sergio, Gillette, Thomas G., Hill, Joseph A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836394/
https://ncbi.nlm.nih.gov/pubmed/27048565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aad5736
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