Inhibition of class I histone deacetylases blunts cardiac hypertrophy through TSC2-dependent mTOR repression

Altering chromatin structure through histone posttranslational modifications has emerged as a key driver of transcriptional responses in cells. Modulation of these transcriptional responses by pharmacological inhibition of class I histone deacetylases (HDACs), a group of chromatin remodeling enzymes...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Signal
Main Authors: Morales, Cyndi R., Li, Dan L., Pedrozo, Zully, May, Herman I., Jiang, Nan, Kyrychenko, Viktoriia, Cho, Geoffrey, Kim, Soo Young, Wang, Zhao V., Rotter, David, Rothermel, Beverly A., Schneider, Jay W., Lavandero, Sergio, Gillette, Thomas G., Hill, Joseph A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836394/
https://ncbi.nlm.nih.gov/pubmed/27048565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aad5736
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados