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Suppression of Class I and II Histone Deacetylases Blunts Pressure-Overload Cardiac Hypertrophy

BACKGROUND: Recent work has demonstrated the importance of chromatin remodeling, especially histone acetylation, in the control of gene expression in the heart. In cell culture models of cardiac hypertrophy, pharmacological suppression of histone deacetylases (HDACs) can either blunt or amplify cell...

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Main Authors: Kong, Yongli, Tannous, Paul, Lu, Guangrong, Berenji, Kambeez, Rothermel, Beverly A., Olson, Eric N., Hill, Joseph A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2006
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4105979/
https://ncbi.nlm.nih.gov/pubmed/16735673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.106.625467
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