Foxo Transcription Factors Blunt Cardiac Hypertrophy by Inhibiting Calcineurin Signaling

BACKGROUND: Cellular hypertrophy requires coordinated regulation of progrowth and antigrowth mechanisms. In cultured neonatal cardiomyocytes, Foxo transcription factors trigger an atrophy-related gene program that counters hypertrophic growth. However, downstream molecular events are not yet well de...

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Autores principales: Ni, Yan G., Berenji, Kambeez, Wang, Na, Oh, Misook, Sachan, Nita, Dey, Asim, Cheng, Jun, Lu, Guangrong, Morris, David J., Castrillon, Diego H., Gerard, Robert D., Rothermel, Beverly A., Hill, Joseph A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2006
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118290/
https://ncbi.nlm.nih.gov/pubmed/16952979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.106.637124
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