Sustained hemodynamic stress disrupts normal circadian rhythms in calcineurin-dependent signaling and protein phosphorylation in the heart

RATIONALE: Despite overwhelming evidence of the importance of circadian rhythms in cardiovascular health and disease, little is known regarding the circadian regulation of intracellular signaling pathways controlling cardiac function and remodeling. OBJECTIVE: To assess circadian changes in processe...

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Main Authors: Sachan, Nita, Dey, Asim, Rotter, David, Grinsfelder, D. Bennett, Battiprolu, Pavan K, Sikder, Devanjan, Copeland, Victoria, Oh, Misook, Bush, Erik, Shelton, John M., Bibb, James A., Hill, Joseph A., Rothermel, Beverly A.
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042501/
https://ncbi.nlm.nih.gov/pubmed/21233454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.110.235309
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